Cetrotide® is a gonadotropin-releasing hormone (GnRH) antagonist used to control hormone responses, which impact the development of eggs.
Specifically, Cetrotide® helps delay a hormonal event known as the LH (luteinizing hormone) surge, which can result in premature ovulation. Cetrotide® works by directly blocking the trigger effect of GnRH, which controls the secretion of LH. This blocking action is designed to stop a possible LH surge before it begins, allowing eggs to reach the level of development needed for fertilization.
Indication
Cetrotide (cetrorelix acetate for injection) is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Important Safety Information
Cetrotide should only be prescribed by doctors specializing in infertility or reproductive health. Cetrotide can cause serious side effects including ovarian hyperstimulation syndrome (OHSS), with or without blood vessel and lung complications, and multiple births. Cetrotide should not beused in women who, are allergic to cetrorelix acetate, mannitol or exogenous peptide hormones (medicines similar to Cetrotide), who have kidney disease, are pregnant or think they are pregnant, or are breast-feeding. mild and short-lasting injection reactions like reddening, itching and swelling at the injection sites have occurred in women using Cetrotide. nausea and headache have also been reported. Please see the full prescribing information for more information.
This information is not intended to replace discussion with your doctor. See full prescribing information for complete disclosure.