The Merck Group Website
The Merck Group Website

Ovidrel® PreFilled Syringe (choriogonadotropin alfa injection)

Ovidrel® PreFilled Syringe contains recombinant hCG, an injectable hormone. This is the hormone that causes eggs to finish maturing and be released. Ovidrel® PreFilled Syringe is used in infertility treatment cycles following treatment with products containing human follicle stimulating hormone, such as Gonal-f® (follitropin alfa for injection).
The hormone in the Ovidrel® PreFilled Syringe is manufactured to meet standards for quality and purity.
However, following our commitment to the area of reproductive health, Ovidrel® PreFilled Syringe is the only hCG available for subcutaneous (just under the skin) injection in the United States.
Ovidrel® PreFilled Syringe is indicated for the induction of final follicular maturation and early luteinization in infertile women who have undergone pituitary desensitization and who have been appropriately pretreated with follicle stimulating hormones as part of an Assisted Reproductive Technology (ART) program such as in vitro fertilization and embryo transfer. Ovidrel® PreFilled Syringe is also indicated for the induction of ovulation (OI) and pregnancy in anovulatory infertile patients in whom the cause of infertility is functional and not due to primary ovarian failure.
Important Safety Information
Ovidrel® PreFilled Syringe should only be used by physicians who are thoroughly familiar with infertility problems and their management. Ovidrel® PreFilled Syringe is a potent gonadotropic substance capable of causing Ovarian Hyperstimulation Syndrome (OHSS) in women with or without pulmonary or vascular complications.
Ovidrel® PreFilled Syringe is contraindicated in women who exhibit prior sensitivity to hCG preparations or their ingredients, primary ovarian failure, uncontrolled thyroid or adrenal dysfunction and pregnancy. Women who are nursing should also not use Ovidrel.
The most common side effects in women using Ovidrel® PreFilled Syringe include abdominal pain, injectionsite reactions, nausea and vomiting. Reports of multiple births have been associated with Ovidrel® PreFilled Syringe treatment.
For complete product details, see the Full Prescribing information.
This information is not intended to replace discussion with your doctor. See full prescribing information for complete disclosure.


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