Indication
Rebif® (interferon beta-1a) is used to treat relapsing forms of MS to decrease the frequency of relapses and delay the occurrence of some of the physical disability that is common in people with MS.
Rebif is not approved for treatment of chronic progressive MS.
Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack by prescription only.
Important Safety InformationRebif is not approved for treatment of chronic progressive MS.
Rebif is available in 22 mcg and 44 mcg prefilled, preassembled syringes and a titration pack by prescription only.
Before beginning treatment, patients should discuss with their doctor the potential benefits and risks associated with Rebif.
Let your doctor know:
If you have a history of depression, seizures, liver disease, thyroid problems, or blood cell count or bleeding problems, or if you have had previous allergic reactions to medications.
About all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Rebif and other medicines may affect each other, causing serious side effects.
Before you take any new medicines.
Rebif is not recommended for women who are or plan to become pregnant.
If you have a history of depression, seizures, liver disease, thyroid problems, or blood cell count or bleeding problems, or if you have had previous allergic reactions to medications.
About all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Rebif and other medicines may affect each other, causing serious side effects.
Before you take any new medicines.
Rebif is not recommended for women who are or plan to become pregnant.
Potential serious side effects of Rebif include:
Depression and risk of suicide
Liver problems
Risk to pregnancy
Injection-site problems
Severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.
The most common side effects with Rebif are:
Liver problems
Risk to pregnancy
Injection-site problems
Severe allergic reactions. Allergic reactions are rare and may be associated with difficulty in breathing and loss of consciousness, which require immediate medical attention.
The most common side effects with Rebif are:
Injection-site reactions
Flu-like symptoms (fever, chills, muscle aches, tiredness)
Depression
Abdominal pain
Increased liver enzymes
Blood cell count decreases
Let your doctor know if you have any of these symptoms or feel sad, tired, hot or cold, or experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).
Flu-like symptoms (fever, chills, muscle aches, tiredness)
Depression
Abdominal pain
Increased liver enzymes
Blood cell count decreases
Let your doctor know if you have any of these symptoms or feel sad, tired, hot or cold, or experience hives, rashes, bruising, yellowing of the skin, or a change in body weight (gain or loss).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For more information on Rebif visit www.rebif.com or refer to full prescribing information for Rebif®. Patients should be instructed to read the Medication Guide accompanying the product and talk to their doctor.
This information is not intended to replace discussions with your doctor. For additional information about Rebif, please consult the Prescribing Information and Medication Guide and talk to your doctor. You can also call toll-free 1-877-44-REBIF (1-877-447-3243). Rebif is available by prescription only.
